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The two main ingredients of Joint Formula are Andrographis Paniculata and Hyaluronic Acid (HA) in a composition of 250 mg and 30 mg respectively. It includes Rice Powder, Gelatin, Magnesium Stearate, and Silica.
Andrographis paniculata, commonly known as creat or green chireta, is an annual herbaceous plant in the family Acanthaceae, native to India and Sri Lanka. It is widely cultivated in Southern and Southeastern Asia, where it has been traditionally been believed to be a treatment for bacterial infections and some diseases. Andrographis paniculata is called “King of Bitters” used to modulate inflammation in musculoskeletal and brain & nervous tissue. Andrographis paniculata has been used for hundreds of years in traditional Asian medicine systems such as Ayurveda and Chinese medicine, and clinical trials have borne out its efficacy in reducing swelling and pain in the joints.
Degenerative joint disease(DJD), often called osteoarthritis is characterized by the progressive and permanent degradation of articular cartilage; its erosion can cause joint inflammation and pain, decrease mobility, and reduce the performance of physical activity in humans. It was noted that andrographolides could have changed this condition.
andrographolides produced by the Andrographis paniculata to be a potent inhibitor of Metalloproteinases (MMPs), an important group of enzymes which are involved in the cartilage degradation in the joints. The catabolic effectors are responsible for triggering the over synthesis of matrix metalloproteinases (MMPs), the cartilaginous degrading enzymes, in chondrocytes, and the resident synovial cells. These lead to progressive loss of cartilage matrix biomolecules including aggrecan, hyaluronan, and collagen. Andrographis paniculata, have been reported to exert potent anti-inflammatory activity and reduce MMPs expression. By inhibiting cartilage matrix-degrading enzymes (MMPs), andrographolides protect chondrocytes from oxidative stress injury and help regulate the inflammatory response and prevent cartilage destruction by reducing collagen and hyaluronic acid loss from the joint’s cartilage. Furthermore, it has been observed that andrographolides may play a very supportive role in maintaining proper joint structure and function.
Hyaluronic acid is a substance that is naturally present in the human body. It is found in the highest concentrations in fluids around the eyes and joints. It works as a cushion and lubricant in the joints. HA plays one of the most important roles in our joints that make up the Synovial fluid, which cushions all of our joints. The synovial fluid is responsible for helping to act as the shock absorber in joints as well as keep the joint cartilages hydrated. Patients with osteoarthritis have been found to have a reduced amount of hyaluronic acid in the synovial fluid around the joints. It is also affected by compression by breaking down the HA molecules and aging by reducing the body’s ability to produce HA. The reason for combine Hyaluronic acid with anti-inflammatories is it may provide the most therapeutic effect to relieve the pain of osteoarthritis.
It is recommended to use the capsules for at least 90 days.
The ingredients of the Joint Formula are balanced to ensure efficacy and safety.
It helps provide lubrication to areas where synovial fluid has escaped that ultimately causes stress on the joints.
It helps people overcome uncomfortable movements easily due to stiff joints.
A perfect solution to cure the effects of arthritis and other degenerative diseases without any use of chemicals or drugs.
Reduces symptoms of arthritis and other bone and muscular pains
Penetrates tissues to heal joints and soothe inflammation.
Joint Formula can help people think and build positive thoughts.
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